承担的学术研究课题
1.??????? 白细胞介素-10对大鼠肝星状细胞生物学活性的影响(39970722) 国家自然科学基金2000.1-2002.12(负责人)
2.??????? 原发性肝癌新的特异性诊断与免疫治疗研究 卫生部临床重点学科? 2001.6-2004.7(负责人)
3.??????? 人乙肝病毒表面抗原刺激的树突细胞诱导的肝癌的免疫治疗(20010001064) 2001年教育部高校博士点基金? 2001.1-2003.12? (负责人)
4.??????? IL-10/PKC通路对肝星状细胞激活的调节作用(30271270) 国家自然科学基金2003.1-2005.12? (负责人)
5.??????? 核转录因子PPARγ对肝星状细胞激活的调节作用(30371387)国家自然科学基金? 2004.1-2006.12(负责人)
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近五年的代表性论文
1.??????? Mou D.C., Cai S.L., Leng X.S., et al. Evaluation of MAGE-1 and MAGE-3 as tumor-specfic makers to detect blood dissemination of hepatocellular carcinoma cells. Br J Cancer. 2002;86(1):110-116.
2.??????? 冷希圣,翁山耕,李涛等. 大鼠肝星状细胞系的建立及其生物学特性的研究. 解剖学报,2003,34(3):269-274
3.??????? Zhao L, Mou DC, Leng XS, Peng JR, Wang WX, Huang L, Li S, Zhu JY. Expression of cancer-testis antigens in hepatocellular carcinoma. World J Gastroenterol 2004;10(14):2034-2038
4.??????? Cheng J, Leng X, Cai S, Cao Z, Cao G, Du R. Detection of point mutations of Bcl 10 gene in hepatacellular carcinoma tissues:46 cases report. Human Mutation, 2000, Volume 15, Issue 5, Pages 482-483
5.??????? Mai Zhou, JI-Run Peng, Hua-Gang Zhang, Hong-Xia Wang,? Zhao-Hui Zhong, Xin-Ying Pan, Wei-Feng Chen, Xi-Sheng Leng. Identification of two naturally presented MAGE antigenic peptides from a patient with hepatocellular carcinoma by mass spectrometry. Immunology Letters,2005;99:113-121.
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